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Post by vtallison on Mar 13, 2008 5:17:08 GMT -5
In Jan my daughter started accutane. She has severe cystic acne. My ex husband signed the consent and I had no idea that she was going to take this specific drug and I did not know until after she was on it. 6 weeks later after an increase in dosage from 60 mg to 90 mg a day she was sent to the ER with a glucose level of over 600 and has been diagnosed with type 1 diabetes. In the Roche literature they say there is no causal effect. In some lit there is listed diabetes as a rare but severe side effect. Does anyone know if there is a list of documented cases of getting type 1 while using accutane?
Thanks
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Post by Kate on May 6, 2010 15:52:44 GMT -5
I've been looking up this link myself. What I've found so far (I'm at Uni, can access primary literature, but no expertise in this area myself) there is a link between insulin resistance worsening reversibly because of something to do with metabolism in the liver and this is why type ii diabetics are monitored on it. Then there was one paper from 2009 where a 28yo patient recently completed a course of isotreitinion (=roaccutane) and developed diabetes i a few months after. This was claimed to be the first case of a link, and they describe it as "clinically unmasking" the latent adult diebetes. Don't know if you can access it: care.diabetesjournals.org/content/32/8/e99.extract I don't know what that means, it accelerated an inevitable eventual development, or indirectly caused it, or even directly caused it, or what. Sorry I can't be more helpful - I am still looking up myself. Good luck finding answers! |
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Post by fghhgfgh on Sept 7, 2018 20:18:35 GMT -5
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