pinched face since roa!!!

[Roapoisoned]

Hello max
I have a question: Since I have taken roa I have a pinched face and my skin and hairs all of my body aren't any more very good looking...they are ugly because of lack of water in my skin and hairs!! But what is the reason to this lack of water? Do you know that? Can you help me??? Lack of HGH? Or what? What could it be? I suffer and can't look me anymore in the mirror!!! I have no girls anymore since the roa!!
Please help me
Is it irreversible?

[Max]

Roapoisoned,

I do not recommend any treatment for your problems. This forum is non-commercial, and not associated with any sales of any particular products.

Generally can be said, that the more information and biochemical knowledge you have, the more cautious you act, regarding any substance. I suggest you bring the information from this forum and other sources to your doctor, discuss a profile of your symptoms, get results from lab-tests, and find an adequate treatment.

Generally can be said about the accutane induced skin-conditions, that they may depend on:

- lack of pigmentation, related to an induced vitamin a deficiency (however, the half life of vitamin a is quite long, and it may therefore take months until cleared after (Ro)accutane exposure - once cleared, the deficit is present)
- immune-related skin disorder
- lack of fat-metabolism, and hormonal deficits
- disruptions in cell-regeneration, metabolism in skin, ph in the skin
- liver malfunction (a more pronounced effect on the liver than in the average case)
- other non-specified, but explainable reasons, including allergies

Whether permanent skin-damage or not: nothing is entirely static. Permanent damage (defined as currently non-treatable) in for example pigmentation, that is non-related to vitamin A-deficiency can not be excluded.

/Max

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ISOTRETINOIN and depression risk : suggestion to reproduct study about this hypothesis, in order to infirm or confirm it.

cf mail sent to pharmaco-epidemiologics searchers :
www.cjoint.com/doc/18_08/HHDvpcJ5fSb_IsotretinoineMail-.pdf
. in open texte :
www.cjoint.com/c/HGzoz6KDvvb


- ALL THIS SITE IS IN THIS PDF : Last version of "State of the knowledge about the side effects of Roaccutane
(isotretinoin): review of the scientific literature":
www.cjoint.com/doc/18_08/HHDvuUoSvXb_-ScientificStudiesOnIsotretinoinCompleted.pdf
. in open texte :
www.cjoint.com/c/HGyw0KRNVNj
informations of english wikipédia and traduct in french ( to integrate):
www.cjoint.com/doc/18_09/HIhwCR37gZb_ar13ciswikienglishtraductionfran%C3%A7ais.pdf


- last version of french abstract :
www.cjoint.com/doc/18_08/HHviDebLU2b_HGyxgkr8vij-résuméétatsdesconnaissancessurlisotretinoine.pdf
. in open texte :
www.cjoint.com/c/HGyxgkr8vij

- english abstract :
www.cjoint.com/doc/18_07/HGxqLx3KRPj_7777StateOfTheKnowledgeAboutIsotretinoinAbstract7777.pdf
. in open texte
www.cjoint.com/c/HGyw2ZHughj


- extrapolation of Swissmédics data ( french):
www.cjoint.com/doc/18_07/HGxu63wZYij_ExtrapolationStatistiquesSwissm%C3%A9dic2012.pdf
. open texte :
www.cjoint.com/c/HGywYwNXEYj


- extrapolation of Swissmédics data ( english):
www.cjoint.com/doc/18_07/HGxuQI7XCVj_StatisticCalculPharmacovigilance.pdf
open texte :
www.cjoint.com/c/HGyw6ztm3dj