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Post by Max on Jul 8, 2005 7:30:29 GMT -5
A decreased hippocampal cell-survival, and loss of hippocampal cells, have been found in rats exposed to (Ro)accutane [1 and 4]. The hippocampus is an area that in human is suggested to be involved in short term memory storage and retrieval [2, 3 and more].
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Post by Max on Jul 8, 2005 7:32:02 GMT -5
b
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Post by Max on Jul 8, 2005 7:32:19 GMT -5
c
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Post by Max on Jul 8, 2005 7:32:47 GMT -5
References:
[1] Sakai Y, Crandall JE, Brodsky J, McCaffery P. 13-cis Retinoic acid (accutane) suppresses hippocampal cell survival in mice. (2004) Ann N Y Acad Sci. Jun;1021:436-40.
[2]
[3]
[4] Crandall J, Sakai Y, Zhang J, Koul O, Mineur Y, Crusio WE, McCaffery P. 13-cis-retinoic acid suppresses hippocampal cell division and hippocampal-dependent learning in mice. (2004) Proc Natl Acad Sci U S A. Apr 6;101(14):5111-6.
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Post by jhkhj on Sept 7, 2018 19:37:54 GMT -5
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